INFLUENCIA DEL MÉTODO DE CONJUGACIÓN EN LAS PROPIEDADES INMUNOLÓGICAS DE CONJUGADOS DE STREPTOCOCCUS PNEUMONIAE SEROTIPO 19A

• Lic. Patricia Gonzalez

• Spanish / Español

• método de conjugación
• streptococcus pneumoniae

Streptococcus pneumoniae bacteria causes various infections and severe invasive processes in humans that generate nearly one million deaths annually. Serotype 19A has a high incidence worldwide and in Cuba. Finlay Vaccine Institute developes a decavalent conjugate vaccine, which includes this serotype. Conjugation methods introduces modifications that may affect antigenic and immunological properties of polysaccharide. In the present work, glycoconjugates from serotype 19A to tetanus toxoid were...