Proteomic Characterization of Outer Membrane Vesicle Vaccine From Vibrio cholerae.

• MsC. Maria de Los Angeles Padron Collazo

• English

• outer membrane proteins
• proteomic methods
• vaccines
• vibrio cholerae

Cholera epidemics affect a large number of African, Asian and Caribbean countries. The climatic changes and the constant migrations cause that this disease spreads so, it is necessary to obtain protective vaccines. In the present work, a new vaccine of outer membrane vesicles (OMV) from V. cholerae O1 biotype El Tor serotype Ogawa strain C7258 at Finlay Institute of vaccines (Cuba) was characterized by proteomic methods. We identified 53 proteins present in the OMV (approximate ratio of 4 protei...