Trabajos

Increased antimicrobial properties of the C terminal fragment of the natural antimicrobial peptide panusin

  • Lic. Amanda Vázquez
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Marine invertebrates are a rich and unexploited source of bioactive compounds. Natural antimicrobial peptides from these organisms are amongst the most promising molecules nowadays to face the antimicrobial resistance problem. Panusin is an antimicrobial peptide isolated from the hemocytes of the spiny lobster Panulirus argus, that displays potent and wide spectrum antimicrobial activity and non-hemolytic effect. In order to obtain an optimized structure derived from panusin, we have synthetized...

Cuban flora species as a potential source of DNA protective compounds

  • Prof. Fabiana Fuentes León
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Environmental exposure to genotoxic agents represents a major health concern for modern society. DNA damage could lead to mutations, which accumulative effect is closely related to degenerative and lethal diseases, such as cancer. Because of their structural and chemical diversity natural products play a fundamental role in pharmaceutical sciences for novel drug discovery. The present review article focuses on pre-clinical studies done with some species from Cuban flora that have been tested wit...

IN VITRO ANTIVIRAL ACTIVITY OF PHYLLANTHUS ORBICULARIS KUNTH DERIVED POLYPHENOLS.

  • Dr. Annele Roque Quintero
  • 26/06/2019 14:00

Despite the availability of an effective vaccine, hepatitis B virus (HBV) and herpesvirus (HSV) infections remain one of the foremost public health problems in the world. The antiviral activity of P. orbicularis, a Cuban endemic plant, has previously been reported but data on its phytochemical characterization and elucidation of antiviral metabolites are still lacking. In this work we identified the main phytochemical compounds responsible for the anti-HBV activity through a bioactivity-guided p...

ANTIVIRAL ACTIVITY OF MARINE ALGAE

  • Dr. Annele Roque Quintero
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Marine ecosystems are a promising source of living organisms that exhibit a wide spectrum of applications in the field of Biomedicine since they are sources of compounds with multiple biological activities such as antimicrobial, antifungal, antioxidant, antitumor, antiviral, among others. Marine algae have a varied biochemical composition and are able to synthesize metabolites with antiviral activity, among which flavonoids, tannins, peptides and polysaccharides such as carrageenans, alginates, ...

GENOTOXIC AND ANTIGENOTOXIC ACTIVITY OF Bryothamnion triquetrum AND Halimeda incrassata SEAWEEDS EXTRACTS

  • Ángel Sánchez Lamar
  • 26/06/2019 14:11

The ultraviolet (UV) component of sunlight is high on the earth surface, especially at low latitudes, raising the risk of skin diseases, including cancer. The use of natural compounds is a strategy to protect people against UV damage. Seaweeds are becoming increasingly influential in the food industry, and are also used in the pharmacy and cosmetic industries, due to several bioactive demonstrated properties. This work analyzed the genotoxic and protective effects of the aqueous extracts of two ...

ETHYL ACETATE FRACTION FROM KIGELIA AFRICANA (BIGNONIACEAE) FLOWERS SHOWED POTENT ANTIOXIDANTS PROPERTIES AND DUAL VASCULAR EFFECTS

  • Prof. Enoel Hernández Barreto
  • 26/06/2019 14:49
  • Restaurante "El Tesico"

The objectives of this study were to explore its vascular and antioxidant properties on isolated rat aorta and cell free antioxidant systems. Methods: Plant material: Fresh flowers were collected in the forest surrounding Botanical Garden of Central University of Las Villas. Phytochemical procedure: Etanolic (EF), ethylacetate (EAF) and butanolic (BF) fractions from flowers were obtained by soxhlet apparatus method with EtOH. The initial crude ethanolic extract was subject to sequential liquid-l...

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