Trabajos

Properties of complex sugars extracted from sugar maple bark

  • Dr. Tatjana Stevanovic Janezic
  • 26/06/2019 09:44
  • Restaurante "El Tesico"

The sugar maple is a native species of northeastern North America and is widely appreciated and exploited for its sap, which is concentrated to produce maple syrup. However, its bark is not widely used, despite its content of a variety of bioactive compounds which could be applied in health products. Apart from polyphenols, higher molecular weight compounds such as oligo- and polysaccharides have been less explored so far. The aim of this investigation was to isolate and characterize a complex s...

NUEVOS DITERPENOS AISLADOS DE LA CORTEZA DE Gymnanthes lucida Sw. (YAITÍ) (EUPHORBIACEAE)

  • Dr. Ania Ochoa Pacheco
  • 26/06/2019 10:35
  • Restaurante "El Tesico"

Gymnanthes lucida Sw. (Excoecaria lucida Sw. ¨sin.¨) (yaití) (Euphorbiaceae) es una especie vegetal que la población cubana usa con fines medicinales, como antimicrobiano, antiasmático, para el dolor de muelas y destrucción de callos; sin embargo existe una insuficiente información científica fitoquímica y farmacológica que sustente sus usos medicinales tradicionales. El presente trabajo aborda el aislamiento e identificación estructural de compuestos presentes en un extracto etanólico de la cor...

BIOASSAY-FRACTIONATION EVALUATION OF ANTIPROTOZOAL ACTIVITY OF THE LEAVES OF CROTON LINEARIS JACQ.

  • Dr. Jesús García Díaz
  • 26/06/2019 10:40
  • Restaurante "El Tesico"

Leaves of Croton linearis, known as “rosemary”, are widely used in folk medicine in Caribbean countries to treat fever and colds (associated to infections), that’s why in the present work we accomplish to evaluate the in vitro antimicrobial activity of extracts and fractions derived from C. linearis leaves. Bioassay-guided fractionation and isolation of compounds from an ethanolic extract of C. linearis, using flash chromatography and semi-preparative HPLC-DAD-MS (High Performance Liquid Chromat...

ENDEMIC PLANTS OF THE GENUS PHYLLANTHUS AS POTENTIAL SOURCES FOR OBTAINING NATURAL ANTIVIRALS

  • Dr. Annele Roque Quintero
  • 26/06/2019 10:55
  • Restaurante "El Tesico"

Viruses are the etiological agents of numerous diseases of importance to human and animal health. There is a need to seek for less toxic antiviral drugs, with more than one mechanism of action that prevents the emergence of resistance, as well as being accessible to the population in need. The Cuban flora has a wide biodiversity and species richness, whose biological activities are not completely characterized. Among them stands out the genus Phyllanthus, which has been used in the Traditional M...

OPTIMIZATION OF FLAVONOIDS EXTRACTION FROM ANNONA MURICATA L. LEAVES

  • MsC. Suslebys Salomón Izquierdo
  • 26/06/2019 11:15
  • Restaurante "El Tesico"

Introduction: Annona muricata L. (soursop) is used in ethnomedicine for the treatment of various diseases. Leaves of this species have been found to contain flavonoids, which are compounds with antidiabetic, antioxidant and anti-inflammatory properties. Objective: optimization of operational parameters on the solid–liquid extraction of flavonoids from A. muricata leaves. Methods: Evaluation of the operational variables was based on Composite Center Design (CCD) of Response surface methodology (R...

SOLUCIÓN VISCOSA DE ALOE: VALIDACIÓN DE MÉTODO ANALÍTICO Y ESTUDIO DE ESTABILIDAD.

  • Claudia Mora
  • 26/06/2019 11:35
  • Restaurante "El Tesico"

La Solución Viscosa de Aloe se comercializa desde hace varios años en nuestro país, como antiulceroso y se produce en la Estación Experimental de Plantas Medicinales “Dr. Juan Tomás Roig” perteneciente al CIDEM. Exigencias actuales en el ámbito nacional e internacional, para productos naturales, reportan la necesidad de establecer metodologías analíticas para la cuantificación de los compuestos de interés. Se desarrolló un método analítico por espectrofotometría aplicable al control de la calida...

Targeting ovarian cancer cell cytotoxic drug resistance phenotype with Xanthium strumarium L extract

  • Janet Piloto Ferrer
  • 26/06/2019 11:55
  • Restaurante "El Tesico"

Background: Emerging drugs aim at targeting the genomic integrity and replication machinery in ovarian cancer. Whereas the antiproliferative activity of Xanthium strumarium L extract (XFC) was recently attributed to alterations in the mitotic apparatus of Chinese hamster ovary (CHO) epithelial cells. XFC capacity to target ovarian cancer cells is unknown. Purpose: Here, we first tested whether XFC impacted on human breast (MCF-7, MDA-MB-231), colorectal (HT-29, C2BBe1) and ovarian cancer cells p...

TAMIZAJE FITOQUÍMICO Y HUELLA DIGITAL DE EXTRACTOS FLUIDOS DE PLUCHEA CAROLINENSIS (JACQ.) G. DON, ASTERACEAE (SALVIA DE PLAYA).

  • Alix Paret Gómez
  • 26/06/2019 12:15
  • Restaurante "El Tesico"

Una de las plantas más utilizadas en la fitoterapia cubana es Pluchea carolinensis (Jacq.) G. Don (salvia playa), de la cual se han reportado propiedades como antiinflamatoria, antipirética, antialérgica, hepatoprotectora, anti-trombótica, anti-neoplásica, anti-úlcerosa, estrogénica, hipoglucemiante, expectorante, anti-hemorrágica y diurética. Este trabajo persigue como objetivo hacer un análisis fitoquímico previo y una huella dactilar preliminar de diferentes extractos fluídicos de hojas de P....

DESARROLLO FARMACÉUTICO DE UNGÜENTO DE QUITOSANA 1% PARA EL TRATAMIENTO DE QUEMADURAS

  • Lic. Niurys Mantilla García
  • 26/06/2019 12:35
  • Restaurante "El Tesico"

La quitosana es un polímero natural, biodegradable, biocompatible, de baja toxicidad, renovable y factible económicamente con propiedades antibacterianas, antifúngicas, tensoactivas, antitumorales, mucoadhesivas y cicatrizantes. Se aplicó un diseño de mezcla D-optimal, modelo lineal para optimizar la composición del ungüento de quitosana al 1%, derivada de quitina de langosta (Panulirus argus). Los componentes de variación fueron la concentración de hidróxido de sodio, lanolina anhidra y agua de...

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