Increased antimicrobial properties of the C terminal fragment of the natural antimicrobial peptide panusin

• Lic. Amanda Vázquez
• 26/06/2019 14:00
• Restaurante "El Tesico"

• Póster digital
• English

• antimicrobial peptide
• bacterial permeabilization
• lipopolysaccharide
• selective citotoxicity

Marine invertebrates are a rich and unexploited source of bioactive compounds. Natural antimicrobial peptides from these organisms are amongst the most promising molecules nowadays to face the antimicrobial resistance problem. Panusin is an antimicrobial peptide isolated from the hemocytes of the spiny lobster Panulirus argus, that displays potent and wide spectrum antimicrobial activity and non-hemolytic effect. In order to obtain an optimized structure derived from panusin, we have synthetized...