Preparation, Characterization and in vitro Evaluation of 5-Fluorouracil loaded polyvinylpyrrolidone nanogels for injectable application.

• Prof. Adrian Alejandro Ges Naranjo

• English

• cancer
• cytotoxicity
• drug delivery
• gamma irradiation
• nanogel
• neutrophil

Many anticancer agents strongly cause noxious effects to human body and therefore the development of suitable delivery systems for these antineoplastic drugs has received a noteworthy attention in cancer research. Nanogels—particles of polymer gels having the dimensions in the order of nanometers—are promising novel pharmaceutical carriers for biologically active agents, biomacromolecules and can be modified to incorporate ligands for targeted drug delivery. The purpose of this study was to form...