Síntesis de conjugados de polisacáridos capsulares de Streptococcus pneumoniae a toxoide tetánico (TT) vía reacciones click catalizadas mediante novedosas nanopartículas de cobre.

• Lic. Dayan Viera Barredo

• English

• click chemistry
• conjugados
• nanoparticulas de cu@fe
• pneumoniae

Streptococcus pneumoniae is one of the fundamental causes of pneumonia, meningitis, otitis and sepsis worldwide. The main strategy to prevent these diseases is based on immunization with conjugate vaccines, where the capsular polysaccharide (PsC) is covalently linked to a carrier, usually a protein. These vaccines manage to induce powerful immune responses and generate immunological memory against the bacteria. Nowadays, the main aim is to improve the pharmacological properties of the conjugate ...