Trabajos

Properties of complex sugars extracted from sugar maple bark

  • Dr. Tatjana Stevanovic Janezic
  • 26/06/2019 09:44
  • Restaurante "El Tesico"

The sugar maple is a native species of northeastern North America and is widely appreciated and exploited for its sap, which is concentrated to produce maple syrup. However, its bark is not widely used, despite its content of a variety of bioactive compounds which could be applied in health products. Apart from polyphenols, higher molecular weight compounds such as oligo- and polysaccharides have been less explored so far. The aim of this investigation was to isolate and characterize a complex s...

BIOASSAY-FRACTIONATION EVALUATION OF ANTIPROTOZOAL ACTIVITY OF THE LEAVES OF CROTON LINEARIS JACQ.

  • Dr. Jesús García Díaz
  • 26/06/2019 10:40
  • Restaurante "El Tesico"

Leaves of Croton linearis, known as “rosemary”, are widely used in folk medicine in Caribbean countries to treat fever and colds (associated to infections), that’s why in the present work we accomplish to evaluate the in vitro antimicrobial activity of extracts and fractions derived from C. linearis leaves. Bioassay-guided fractionation and isolation of compounds from an ethanolic extract of C. linearis, using flash chromatography and semi-preparative HPLC-DAD-MS (High Performance Liquid Chromat...

ENDEMIC PLANTS OF THE GENUS PHYLLANTHUS AS POTENTIAL SOURCES FOR OBTAINING NATURAL ANTIVIRALS

  • Dr. Annele Roque Quintero
  • 26/06/2019 10:55
  • Restaurante "El Tesico"

Viruses are the etiological agents of numerous diseases of importance to human and animal health. There is a need to seek for less toxic antiviral drugs, with more than one mechanism of action that prevents the emergence of resistance, as well as being accessible to the population in need. The Cuban flora has a wide biodiversity and species richness, whose biological activities are not completely characterized. Among them stands out the genus Phyllanthus, which has been used in the Traditional M...

OPTIMIZATION OF FLAVONOIDS EXTRACTION FROM ANNONA MURICATA L. LEAVES

  • MsC. Suslebys Salomón Izquierdo
  • 26/06/2019 11:15
  • Restaurante "El Tesico"

Introduction: Annona muricata L. (soursop) is used in ethnomedicine for the treatment of various diseases. Leaves of this species have been found to contain flavonoids, which are compounds with antidiabetic, antioxidant and anti-inflammatory properties. Objective: optimization of operational parameters on the solid–liquid extraction of flavonoids from A. muricata leaves. Methods: Evaluation of the operational variables was based on Composite Center Design (CCD) of Response surface methodology (R...

Targeting ovarian cancer cell cytotoxic drug resistance phenotype with Xanthium strumarium L extract

  • Janet Piloto Ferrer
  • 26/06/2019 11:55
  • Restaurante "El Tesico"

Background: Emerging drugs aim at targeting the genomic integrity and replication machinery in ovarian cancer. Whereas the antiproliferative activity of Xanthium strumarium L extract (XFC) was recently attributed to alterations in the mitotic apparatus of Chinese hamster ovary (CHO) epithelial cells. XFC capacity to target ovarian cancer cells is unknown. Purpose: Here, we first tested whether XFC impacted on human breast (MCF-7, MDA-MB-231), colorectal (HT-29, C2BBe1) and ovarian cancer cells p...

ANTIPLATELET ACTIVITY OF CITRUS PLANT EXTRACTS

  • Dr. C. Milagros T Garcia Mesa
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

The antithrombotic efficacy and safety of currently available antiplatelet drugs is limited for different reasons. Therefore, other effective, safe and low-cost therapeutic options are needed The fact that acetyl salicylic acid (ASA), a reference antithrombotic drug, was discovered from Salix alba L. (willow) allows suggesting that new therapeutic options could be developed from other plant species. Nevertheless, “antiplatelet” is not a popular term, being difficult to find clues from Ethnomedic...

Increased antimicrobial properties of the C terminal fragment of the natural antimicrobial peptide panusin

  • Lic. Amanda Vázquez
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Marine invertebrates are a rich and unexploited source of bioactive compounds. Natural antimicrobial peptides from these organisms are amongst the most promising molecules nowadays to face the antimicrobial resistance problem. Panusin is an antimicrobial peptide isolated from the hemocytes of the spiny lobster Panulirus argus, that displays potent and wide spectrum antimicrobial activity and non-hemolytic effect. In order to obtain an optimized structure derived from panusin, we have synthetized...

CELL-FREE SYSTEMS AS AN ALTERNATIVE TO PRODUCE BIOPHARMACEUTICALS

  • MsC. Javier E. Vázquez
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

In recent years, cell-free systems (CFS) has emerged as a powerful technology to satisfy the growing demand for simple and efficient protein production as industrial processes, especially in case of biopharmaceuticals products. Very significant costs reduction, reaction scale (reached the 100 liter recently) and well-controlled reactions conditions are among the major advantages for this production platform compared to in vivo systems. In spite of those promising aspects, CFS has several hurdles...

Cuban flora species as a potential source of DNA protective compounds

  • Prof. Fabiana Fuentes León
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Environmental exposure to genotoxic agents represents a major health concern for modern society. DNA damage could lead to mutations, which accumulative effect is closely related to degenerative and lethal diseases, such as cancer. Because of their structural and chemical diversity natural products play a fundamental role in pharmaceutical sciences for novel drug discovery. The present review article focuses on pre-clinical studies done with some species from Cuban flora that have been tested wit...

ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF EXTRACTS OF THE PLANT ADELIA RICINELLA L.

  • MsC. Clara Azalea Berenguer Rivas
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Adelia ricinella L. is a Caribbean plant used as antipyretic, anti-inflammatory and analgesic, of which there is few phytochemical and pharmacological information to support its traditional uses. In this research the antioxidant and anti-inflammatory activities of three extracts (95% ethanol, 50% ethanol and water) obtained from aerial parts were evaluated using Soxhlet extraction. The main secondary metabolites were determined from qualitative and quantitative point of view. Antioxidant activit...

IN VITRO ANTIVIRAL ACTIVITY OF PHYLLANTHUS ORBICULARIS KUNTH DERIVED POLYPHENOLS.

  • Dr. Annele Roque Quintero
  • 26/06/2019 14:00

Despite the availability of an effective vaccine, hepatitis B virus (HBV) and herpesvirus (HSV) infections remain one of the foremost public health problems in the world. The antiviral activity of P. orbicularis, a Cuban endemic plant, has previously been reported but data on its phytochemical characterization and elucidation of antiviral metabolites are still lacking. In this work we identified the main phytochemical compounds responsible for the anti-HBV activity through a bioactivity-guided p...

ANTIVIRAL ACTIVITY OF MARINE ALGAE

  • Dr. Annele Roque Quintero
  • 26/06/2019 14:00
  • Restaurante "El Tesico"

Marine ecosystems are a promising source of living organisms that exhibit a wide spectrum of applications in the field of Biomedicine since they are sources of compounds with multiple biological activities such as antimicrobial, antifungal, antioxidant, antitumor, antiviral, among others. Marine algae have a varied biochemical composition and are able to synthesize metabolites with antiviral activity, among which flavonoids, tannins, peptides and polysaccharides such as carrageenans, alginates, ...

GENOTOXIC AND ANTIGENOTOXIC ACTIVITY OF Bryothamnion triquetrum AND Halimeda incrassata SEAWEEDS EXTRACTS

  • Ángel Sánchez Lamar
  • 26/06/2019 14:11

The ultraviolet (UV) component of sunlight is high on the earth surface, especially at low latitudes, raising the risk of skin diseases, including cancer. The use of natural compounds is a strategy to protect people against UV damage. Seaweeds are becoming increasingly influential in the food industry, and are also used in the pharmacy and cosmetic industries, due to several bioactive demonstrated properties. This work analyzed the genotoxic and protective effects of the aqueous extracts of two ...

OPTIMIZATION OF MICROWAVE ASSISTED EXTRACTION OF LIPIDS FROM CUCURBITA PEPO L. SEEDS

  • MsC. Suslebys Salomón Izquierdo
  • 26/06/2019 14:23
  • Restaurante "El Tesico"

Lipids from pumpkin seeds, has been widely used in the treatment of prostatic hyperplasia attributed due to its high content in unsaturated fatty acids like linoleic, oleic, palmitic and estearic as the main active principles. This study deals with the optimization of microwave assisted extraction (MAE) of lipids from Cucurbita pepo L. seeds. To evaluate the effect of three independent variables, etanol to plant material ratio, microwave power used for extraction and Irradiation time, Box–Behnke...

AN ETHNOBOTANICAL SURVEY OF MEDICINAL PLANTS USED BY INHABITANTS OF HOLGUÍN, EASTERN REGION, CUBA

  • MsC. Rosalia González Fernández
  • 26/06/2019 14:41
  • Restaurante "El Tesico"

For a long time, medicinal plants have played a very important role to treat various disorders and ailments in people’s health. Nowadays, the use of herbal remedies as a way of treatment is still very important for human beings. Ethnobotanical studies are a valuable tool to achieve the documentation of this ethnomedicinal knowledge. Cuba has a high diversity and endemism of Cuban flora, as well as the wide knowledge of medicinal plants in his inhabitants, that's why the present study is aimed to...

ETHYL ACETATE FRACTION FROM KIGELIA AFRICANA (BIGNONIACEAE) FLOWERS SHOWED POTENT ANTIOXIDANTS PROPERTIES AND DUAL VASCULAR EFFECTS

  • Prof. Enoel Hernández Barreto
  • 26/06/2019 14:49
  • Restaurante "El Tesico"

The objectives of this study were to explore its vascular and antioxidant properties on isolated rat aorta and cell free antioxidant systems. Methods: Plant material: Fresh flowers were collected in the forest surrounding Botanical Garden of Central University of Las Villas. Phytochemical procedure: Etanolic (EF), ethylacetate (EAF) and butanolic (BF) fractions from flowers were obtained by soxhlet apparatus method with EtOH. The initial crude ethanolic extract was subject to sequential liquid-l...

Oxford Biolabs – Natural therapies for hair loss and skin ageing

  • Dr. Thomas Whitfield

Lecture about our company and what we are doing (www.oxfordbiolabs.com) and that we looking for new plant extracts ...

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